While Ozempic has been celebrated as a miracle for weight loss, a massive new study of 150,000 patients reveals a heartbreaking hidden cost: our bones are paying the price for a slimmer silhouette. For many, shedding pounds felt like reclaiming life. But research shows long-term GLP-1 use may increase osteoporosis risks by 30% and accelerate bone softening. The culprit? We aren't just losing fat; we are losing the vital muscle that keeps our skeletons strong. Combined with se

Sometime in my early-ish to mid-forties things started to get weird. I developed severe anxiety, a full night’s sleep became elusive, I felt achy and old, was so fatigued, I gained weight (especially in my belly), I began having spells of vertigo, and overall, just generally didn’t feel at home in my body. None of this had happened before and it all happened without changing any lifestyle or dietary habits. I felt like I was falling apart. Was this the fabled midlife crisis I

Fasting and exercise can boost the longevity hormone FGF21, but what can we eat—or avoid eating—to get similar effects? Over a century ago, fasting was hailed not only as a means of combating “cerebral lassitude,” but also for the “prolongation of healthy longevity.” If that turns out to be true, FGF21 might be a missing link. FGF21 is characterized as a “systemic enhancer of longevity.” It can be boosted through prolonged fasting, but thankfully, there are other, less drasti

What can we do to boost the longevity hormone FGF21? In the year 2000, a new human hormone was discovered. It was the 21st documented fibroblast growth factor, so they called it FGF21. Since its discovery, FGF21 has become recognized as a key agent for the promotion of metabolic and arterial health, leanness, and longevity. Inject it into fat monkeys, and they lose body weight without reducing their food intake. And they don’t just lose a little weight—they have a 27% drop in

John Coykendall of Blackberry Farm gives us his top picks — and shares the most common herb-gardening mistake. We've long celebrated makers in the food and beverage industry who are true experts at their craft. Among them is John Coykendall, resident gardener at Blackberry Farm, a luxurious hotel tucked in the mountains of Tennessee. For 20 years, he's been working the gardens — which power Blackberry's legendary culinary program — and tracking down heirloom seeds, documenti

At a Glance You can take CoQ10 to help decrease migraine headaches by shortening the length and frequency of attacks. CoQ10 might improve your heart health by decreasing an inflammatory marker linked to heart disease. You should talk to a doctor or pharmacist before adding CoQ10 supplements to your routine. Health benefits of coenzyme Q10 (CoQ10) include improved heart health and decreased migraine frequency. CoQ10 may also support energy production in your cells. May Impro

We co-evolved a symbiosis with our good gut bacteria, but we aren’t holding up our end of the bargain. If you look at the classics—the most frequently cited articles in the scientific nutrition literature—the original glycemic index paper ranks tenth, cited more than a thousand times. Learning about fruits, vegetables, and cancer prevention comes in seventh. But hitting the top four, cited more than 2,000 times: “Dietary Modulation of the Human Colonic Microbiota: Introducing

Understanding Chronic Inflammation Inflammation is the body’s natural defense mechanism. When acute, it protects you by removing harmful stimuli and initiating healing. However, when this process persists long-term, it becomes chronic inflammation—a condition linked to major diseases, including rheumatoid arthritis and cardiovascular issues. While nonsteroidal anti-inflammatory drugs (NSAIDs) are the standard treatment, they often come with unwanted side effects. This has led

The so-called optimism bias may get in the way of a healthy lifestyle. Yes, media messages about nutrition are often confusing and inconsistent, but many Americans know what is considered a healthy diet. I mean, does anyone really think drinking brown carbonated sugar water is good for them? The issue is that they don’t appear to be translating their knowledge into action. Why do people have such difficulty changing their dietary behaviors? While ignorance and confusion may p

Like many avid home chefs, I draw my cooking knowledge from myriad sources. My mom’s many lessons in the kitchen when I was a child (and on our phone calls today), videos and recipes on the internet, cookbooks, and advice from colleagues all influence how I cook. While drawing on all these sources helps inspire different ideas and has helped refine my point of view on food, it occasionally allows for some misinformation to slip through the cracks. We’ve all bought into a food